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KMID : 0387719930040010023
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Korean Journal of Blood Transfusion
1993 Volume.4 No. 1 p.23 ~ p.28
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Massive Transfusion in Severance Hospital
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이미경
김현옥/홍성근/권오헌/김진주
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Abstract
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Massive transfusion (MT) was defined as complete replacement of the patient's blood volume within a 24-hour period. Average total blood volume in adults was considered to be 5 liters or 20 units of packed red blood cells and/or fresh frozen
plasma
(FFP). In order to analyze the clinical outcome of massive transfusions and their impact upon the blood bank, we reviewed the medical records of 109 patients who met the criteria for massive transfusion at Severance hospital from January through
December 1991, in a retrospective study.
The individual diagnostic categories were 50% of cardiovascular surgery, 16% of UGI bleeding, 16% of oncology cases and 7% of trauma among these massively transfused patients. The overall survival rate was 70% for the entire group. Survival rates
ranged
from 25% for the obstetric cases to 89% for the cardiovascular surgicla cases. There was no correlation between the survivors and nonsurvivors in the initial hematocrit level and in the average number of units transfused. Transfusion reactions
occurred
in 7.3% of total patients who received massive transfusion. Massive transfusion episodes for these 109 patients (0.7% of the total transfused patients) accounted for at least 8% of the yearly total blood units transfused and therefore represented
a
significant proportion of total blood units transfused and therefore represented a significant proportion of total blood component usage at our hospital.
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